RAB3C (NM_138453) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 25.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_612462 |
| Locus ID | 115827 |
| UniProt ID | Q96E17 |
| Cytogenetics | 5q11.2 |
| RefSeq Size | 1030 |
| RefSeq ORF | 681 |
| Summary | This gene is a member of the RAS oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to the cell surface. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2015 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "RAB3C" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301436 | RAB3C MS Standard C13 and N15-labeled recombinant protein (NP_612462) | 10 ug |
$3,360.00
|
|
| LC408603 | Lyophilized RAB3C HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY408603 | Transient overexpression lysate of RAB3C, member RAS oncogene family (RAB3C) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers
Frick, Sellier, Mackenzie et al
Acta Neuropathol Commun (2018) 6 (1), 72 DOI: 10.1186/s40478-018-0579-0
Frick, Sellier, Mackenzie et al
Acta Neuropathol Commun (2018) 6 (1), 72 DOI: 10.1186/s40478-018-0579-0
AI Summary: OriGene products, specifically pCMV6 plasmids containing C-terminally myc-DDK-tagged cDNAs for human and mouse C9orf72 isoforms, as well as FLAG-tagged human SMCR8 and Rab proteins, were used for expression studies to investigate C9orf72 protein localization, interactions, and levels in this study.
Snippet: pCMV6 containing C-terminally myc-DDK-tagged cDNAs of human C9orf72 variant 1 (NM_145005), human C9orf72 variant 2 (NM_018325), mouse C9orf72 encoding for isoform 1 (NM_001081343), mouse C9orf72 encoding for isoform 2 (BC026738), C-terminally FLAG-tagged human cDNAs of SMCR8, and Rab proteins were purchased from OriGene. cDNAs for C9orf72 were subcloned into pcDNA5/FRT/TO (Invitrogen) with or without myc-DDK-tag. Optimized cDNA for human N-terminally HA-tagged C9orf72 variant 1 cloned in pcDNA3 was described previously [45] and is available through Addgene
Showing 1-1 of 1 papers.
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