PLAUR (NM_002659) Human Recombinant Protein
SKU
TP301222
Recombinant protein of human plasminogen activator, urokinase receptor (PLAUR), transcript variant 1, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 34.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Dimerization assay (confocal) (PMID: 25418095) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002650 |
| Locus ID | 5329 |
| UniProt ID | Q03405 |
| Cytogenetics | 19q13.31 |
| RefSeq Size | 1570 |
| RefSeq ORF | 1005 |
| Synonyms | CD87; U-PAR; UPAR; URKR |
| Summary | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. provided by RefSeq, Jul 2008 |
| Protein Categories | CD Markers, Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PLAUR" proteins (10)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301222 | PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_002650) | 10 ug |
$3,360.00
|
|
| PH317929 | PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_001005376) | 10 ug |
$3,360.00
|
|
| LC400943 | Lyophilized PLAUR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC423709 | Lyophilized PLAUR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC423710 | Lyophilized PLAUR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400943 | Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY423709 | Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY423710 | Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP317929 | Purified recombinant protein of Homo sapiens plasminogen activator, urokinase receptor (PLAUR), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP720329 | Recombinant protein of human plasminogen activator, urokinase receptor (PLAUR), transcript variant 2 | 10 ug |
$275.00
|
|
Citations
Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures
Ge, Siegel, Jordan et al
Biophys. J. (2014) 107 (9), 2101-11 DOI: 10.1016/j.bpj.2014.09.021
Ge, Siegel, Jordan et al
Biophys. J. (2014) 107 (9), 2101-11 DOI: 10.1016/j.bpj.2014.09.021
Cited by 14
AI Summary: OriGene products contributed to this study by providing purified recombinant human uPAR with a C-terminal MYC/DDK tag and the Anti-DDK monoclonal antibody, which were essential for detecting and analyzing uPAR behavior in raft-mimicking lipid mixtures.
Snippet: Purified recombinant Homo sapiens uPAR with C-terminal MYC/DDK tag and Anti-DDK monoclonal antibody were purchased from OriGene Technologies (Rockville, MD). Anti-uPAR (N-terminal) antibody, was purchased from Proteintech (Chicago, IL). ... Cite SaveSaving
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
