Superoxide Dismutase 1 (SOD1) (NM_000454) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 15.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000445 |
| Locus ID | 6647 |
| UniProt ID | P00441 |
| Cytogenetics | 21q22.11 |
| RefSeq Size | 981 |
| RefSeq ORF | 462 |
| Synonyms | ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD; STAHP |
| Summary | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. provided by RefSeq, Jul 2020 |
| Protein Categories | Cytokines, Intracellular Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "Superoxide Dismutase 1" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300725 | SOD1 MS Standard C13 and N15-labeled recombinant protein (NP_000445) | 10 ug |
$3,360.00
|
|
| LC400160 | Lyophilized SOD1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400160 | Transient overexpression lysate of superoxide dismutase 1, soluble (SOD1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP720521 | Recombinant protein of human superoxide dismutase 1, soluble (SOD1) | 10 ug |
$340.00
|
|
| TP750141 | Purified recombinant protein of Human superoxide dismutase 1, soluble (SOD1), full length, with N-terminal His tag, expressed in E. coli, 50ug | 50 ug |
$270.00
|
|
Citations
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