CDK2 (NM_001798) Human Recombinant Protein

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SKU
TP300494
Recombinant protein of human cyclin-dependent kinase 2 (CDK2), transcript variant 1, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC200494 protein sequence
Red=Cloning site Green=Tags(s)

MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVI
HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA
IKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEID
QLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAA
LAHPFFQDVTKPVPHLRL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 33.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001789
Locus ID 1017
UniProt ID P24941
Cytogenetics 12q13.2
RefSeq Size 2301
RefSeq ORF 894
Synonyms CDKN2; p33(CDK2)
Summary This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2014
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Small cell lung cancer
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Other "CDK2" proteins (6)
SKU Description Size Price
PH300494 CDK2 MS Standard C13 and N15-labeled recombinant protein (NP_001789) 10 ug
$3,360.00
LC409442 Lyophilized CDK2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC419741 Lyophilized CDK2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY409442 Transient overexpression lysate of cyclin-dependent kinase 2 (CDK2), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY419741 Transient overexpression lysate of cyclin-dependent kinase 2 (CDK2), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP720187 Recombinant protein of human cyclin-dependent kinase 2 (CDK2), transcript variant 1 10 ug
$340.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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