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CDK2 Mouse Monoclonal Antibody [Clone ID: OTI2D9]

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SKU
TA502935
CDK2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "CDK2 or NM_001798" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2D9
Application FC, IF, Simple Western, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100, Simple Western 1:20-1:50
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CDK2 (NP_001789) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration lot dependent
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 33.7 kDa
Gene Name cyclin dependent kinase 2
Database Link
Background The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. provided by RefSeq
Synonyms CDKN2; p33(CDK2)
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Small cell lung cancer
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Other "OTI2D9" antibodies (4)
SKU Description Size Price
CF502935 Carrier-free (BSA/glycerol-free) CDK2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9) 100 ug
$620.00
TA502935AM CDK2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9), Biotinylated 100 ul
$509.00
TA502935BM CDK2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9), HRP conjugated 100 ul
$509.00
TA502935S CDK2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9) 30 ul
$200.00

file-alt Citations

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors
Singh, Gleason, Fang et al
Nature (2025)
Cited by 21
AI Summary: OriGene’s mouse anti-CDK2 antibody (TA502935) was used in this study to detect CDK2 protein levels, contributing to the analysis of cell cycle regulatory mechanisms affected by cyclin A/B RxL inhibitors.
Snippet: mouse anti-cyclin B (Cell Signaling, 4135 1:1,000), mouse anti-E2F1 (SCBT, sc-251, 1:1,000), mouse anti-cyclin A (Cell Signaling, 4656, 1:1,000), mouse anti-CDK2 (Origene, TA502935), rabbit anti-CDC2 (Cell Signaling 28439). The secondary antibodies used and dilutions were
WB
Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity
Singh, Gleason, Fang et al
bioRxiv (2024)
Cited by 5
Snippet: The primary antibodies and dilutions used were: anti-Myt1 (Fortis Life Sciences A302-424A 1:1000), mouse-anti-cyclin B (Cell Signaling #4135 1:1000), mouse-anti-E2F1 (SCBT #sc-251, 1:1000), mouse-anti-cyclin A (Cell Signaling #4656, 1:1000), mouse anti-CDK2 (Origene TA502935), rabbit anti-Cdc2 (Cell Signaling 28439). …
WB
Expanding the ligandable proteome by paralog hopping with covalent probes
Zhang, Liu, Hirschi et al
bioRxiv (2024)
Cited by 7
Snippet: …Antibodies For western blotting, CDK2 mouse monoclonal antibody (HRP conjugated) [Clone ID: OTI2D9] (Origene, TA502935BM), monoclonal Anti-FLAG M2-peroxidase (HRP) (produced in mouse) (Sigma-Aldrich, A8592). Tissue culture HEK293T (ATCC, CRL-3216) cells were maintained in DMEM supplemented with 10%;For western blotting, CDK2 mouse monoclonal antibody (HRP conjugated) [Clone ID: OTI2D9] (Origene, TA502935BM), monoclonal Anti-FLAG M2-peroxidase (HRP) (produced in mouse) (Sigma-Aldrich, A8592)
FigureFigureFigure
WB
Raltitrexed Inhibits HepG2 Cell Proliferation via G0/G1 Cell Cycle Arrest
Zhao, Zhang, Sun et al
Oncol. Res. (2016) 23 (5), 237-48 DOI: 10.3727/096504016X14562725373671
AI Summary: In this study, OriGene products contributed by providing antibodies against TS, CDK2, p53, and p16, which were used in Western blot analyses to assess the expression of key cell cycle regulatory proteins in HepG2 cells treated with raltitrexed.
Snippet: Bradford assay kit was purchased from Jiancheng Bioengineering (Nanjing, China). Antibodies against TS, CDK2, p53, and p16 were from Origene (Rockville, MD, USA). Anti-cyclin A was purchased from Bioworld Technology (Atlanta, GA, USA). ... Cite SaveSaving
WB
Showing 1-4 of 4 papers.
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