FOXO1 (NM_002015) Human Recombinant Protein

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human forkhead box O1 (FOXO1)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 69.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity In vitro kinase assay substrate (PMID: 29066835)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002006
Locus ID 2308
Refseq Size 5723
Cytogenetics 13q14.11
Refseq ORF 1965
Synonyms FKH1; FKHR; FOXO1A
Summary This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Insulin signaling pathway, Pathways in cancer, Prostate cancer

Citations (1)

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