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PSMD8 (NM_002812) Human Recombinant Protein

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SKU
TP300436
Recombinant protein of human proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8), 20 µg
Size:
20 ug 1 mg 100 ug
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC200436 protein sequence
Red=Cloning site Green=Tags(s)

MYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELNFLPTTGTKLTKQQLILARDILEIGAQWSILRKDIPS
FERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKDIQTNVYIKHPVSLE
QYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFTEATRILFFNTPKKMTDYA
KKRGWVLGPNNYYSFASQQQKPEDTTIPSTELAKQVIEYARQLEMIV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 39.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002803
Locus ID 5714
UniProt ID P48556
Cytogenetics 19q13.2
RefSeq Size 1556
RefSeq ORF 771
Synonyms HEL-S-91n; HIP6; HYPF; Nin1p; p31; Rpn12; S14
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. provided by RefSeq, Jul 2008
Protein Categories Intracellular Proteins
Protein Pathways Proteasome
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Other "PSMD8" proteins (3)
SKU Description Size Price
PH300436 PSMD8 MS Standard C13 and N15-labeled recombinant protein (NP_002803) 10 ug
$3,360.00
LC419092 Lyophilized PSMD8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419092 Transient overexpression lysate of proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8) (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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