DCXR (NM_016286) Human Recombinant Protein

CAT#: TP300023

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Recombinant protein of human dicarbonyl/L-xylulose reductase (DCXR)


 Product Datasheet for 'TP300023'

  View other "DCXR" proteins (8)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human dicarbonyl/L-xylulose reductase (DCXR)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 25.7 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_057370
Locus ID 51181
Refseq Size 860
Cytogenetics 17q25.3
Refseq ORF 732
Synonyms DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR
Summary The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Pentose and glucuronate interconversions

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