Collagen type VI Human Protein

SKU
RA011
Human Collagen Type VI
  $800.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Protein Source Placenta
Concentration 1.13 mg/mL by nanodrop at 205 nm
Purity Human Collagen type VI has been prepared from Human Placenta and is chromatographically and immunologically pure. This product is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with anti-Collagen Type VI. Reaction with Rockland’s anti-Collagen I, II, III, IV or V is negligible.
Buffer 0.5 M Acetic Acid
Preparation Liquid (sterile filtered) fraction.
Recommended Dilution ELISA,Immunohistochemistry,Western Blot
Protein Description Collagen type VI, prepared from human placenta, is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with anti-Collagen Type VI. Reaction with anti-Collagen I, II, III, IV or V is negligible (typically less than 1% cross reactivity was detected by ELISA).
Note Human Collagen type VI purified protein standard has been tested in SDS-PAGE and is used as a control in ELISA and Western blot. Collagen type VI is recognized by type specific anti-collagen antibodies that recognize a native three-dimensional structure.
Storage Store vial at 4° C prior to opening. This product is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Stability Expiration date is six (6) months from date of receipt.
Shipping Blue Ice
Reference Data
RefSeq NP_001839
Locus ID 1291
Cytogenetics 21q22.3
Synonyms Type VI collagen, collagen 6, human collagen, collagen VI
Summary The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. provided by RefSeq, Jul 2008
Protein Categories Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families for immunoprecipitation and for Wwestern blotting., For use as a Control or Standard in Indirect trapping ELISA for quantitation of antigen in serum using a standard curve
Protein Pathways ECM-receptor interaction, Focal adhesion
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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