Hepatitis B Surface Antigen / HBsAg (ad) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Protein Source | Blood |
| Concentration | lot specific |
| Purity | >99% “Ad” subtype purity (ELISA) |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid purified fraction Buffer System: 50 mM Phosphate, pH 7.4 ± 0.2 containing 150 mM Sodium Chloride Preservative: 0.09% Sodium Azide |
| Preparation | Liquid purified fraction |
| Recommended Dilution | ELISA. |
| Protein Description | Hepatitis B Surface Antigen (HBsAg), ad subtype. Inactivation: Heat Inactivated at 60°C for 15 hours. |
| Note | Caution: All human source materials have tested negative for HIV1, HIV2 and HCV antibodies. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious. |
| Storage | Store the antigen at 2-8°C. |
| Stability | Shelf life: six months from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| Synonyms | HBV surface antigen, Hepatitis B Virus |
| Summary | Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. |
| Protein Families | ELISA. |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Kamble, Rane, Breed et al
FEBS Lett. (2020)
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