CSK (NM_001127190) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC225740 |
| Predicted MW | 50.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001120662 |
| RefSeq Size | 2236 |
| RefSeq ORF | 1350 |
| Locus ID | 1445 |
| UniProt ID | P41240 |
| Cytogenetics | 15q24.1 |
| Summary | The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2017 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Neurotrophin signaling pathway, Regulation of actin cytoskeleton |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CSK" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310758 | CSK MS Standard C13 and N15-labeled recombinant protein (NP_004374) | 10 ug |
$3,360.00
|
|
| LC401395 | Lyophilized CSK HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426695 | Lyophilized CSK HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401395 | Transient overexpression lysate of c-src tyrosine kinase (CSK), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426695 | Transient overexpression lysate of c-src tyrosine kinase (CSK), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP310758 | Recombinant protein of human c-src tyrosine kinase (CSK), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP325740 | Recombinant protein of human c-src tyrosine kinase (CSK), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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