CSK Rabbit Polyclonal Antibody

SKU
TA375141
CSK Rabbit polyclonal Antibody
  $410.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, IF, IHC, WB
Recommended Dilution WB,1:500 - 1:1000
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Modification Unmodified
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 51kDa
Gene Name c-src tyrosine kinase
Database Link
Background The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants.
Synonyms MGC117393
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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