VRK3 (NM_016440) Human Mass Spec Standard

SKU
PH324292
VRK3 MS Standard C13 and N15-labeled recombinant protein (NP_057524)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC224292
Predicted MW 52.9 kDa
Protein Sequence
Protein Sequence
>RC224292 protein sequence
Red=Cloning site Green=Tags(s)

MISFCPDCGKSIQAAFKFCPYCGNSLPVEEHVGSQTFVNPHVSSFQGSKRGLNSSFETSPKKVKWSSTVT
SPRLSLFSDGDSSESEDTLSSSERSKGSGSRPPTPKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTL
KRSRVTTSLEALPTGTVLTDKSGRQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKDGR
LFNEQNFFQRAAKPLQVNKWKKLYSTPLLAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSE
RSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPH
EGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGH
WIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVSPYDPIGLPMVP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_057524
RefSeq Size 2129
RefSeq ORF 1422
Locus ID 51231
UniProt ID Q8IV63
Cytogenetics 19q13.33
Summary This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. provided by RefSeq, Jul 2008
Protein Families Druggable Genome, Protein Kinase
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Documents
Resources
Other "VRK3" proteins (8)
SKU Description Size Price
LC414023 Lyophilized VRK3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422459 Lyophilized VRK3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC425502 Lyophilized VRK3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY414023 Transient overexpression lysate of vaccinia related kinase 3 (VRK3), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY422459 Transient overexpression lysate of vaccinia related kinase 3 (VRK3), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY425502 Transient overexpression lysate of vaccinia related kinase 3 (VRK3), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP324292 Recombinant protein of human vaccinia related kinase 3 (VRK3), transcript variant 1, 20 µg 20 ug
$867.00
TP761240 Purified recombinant protein of Human vaccinia related kinase 3 (VRK3), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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