TRAF4AF1 (KNSTRN) (NM_033286) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC222981 |
| Predicted MW | 35.4 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_150628 |
| RefSeq Size | 1763 |
| RefSeq ORF | 948 |
| Synonyms | C15orf23; HSD11; SKAP; TRAF4AF1 |
| Locus ID | 90417 |
| UniProt ID | Q9Y448 |
| Cytogenetics | 15q15.1 |
| Summary | Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase (PubMed:19667759). Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture (PubMed:19667759, PubMed:22110139). The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments (PubMed:21402792). Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division (PubMed:23035123). May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences (PubMed:24718257).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TRAF4AF1" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC409608 | Lyophilized KNSTRN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC428260 | Lyophilized KNSTRN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC428261 | Lyophilized KNSTRN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY409608 | Transient overexpression lysate of chromosome 15 open reading frame 23 (C15orf23), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY428260 | Transient overexpression lysate of chromosome 15 open reading frame 23 (C15orf23), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY428261 | Transient overexpression lysate of chromosome 15 open reading frame 23 (C15orf23), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP322981 | Recombinant protein of human chromosome 15 open reading frame 23 (C15orf23), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
| TP701003 | Purified recombinant protein of Human chromosome 15 open reading frame 23 (C15orf23), transcript variant 3, mutant (S24F), expressed in HEK293 cells, 20ug | 20 ug |
$900.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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