Integrin beta 4 binding protein (EIF6) (NM_181468) Human Mass Spec Standard

SKU
PH320391
EIF6 MS Standard C13 and N15-labeled recombinant protein (NP_852133)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220391
Predicted MW 26.4 kDa
Protein Sequence
Protein Sequence
>RC220391 representing NM_181468
Red=Cloning site Green=Tags(s)

MAVRASFENNCEIGCFAKLTNTYCLVAIGGSENFYSVFEGELSDTIPVVHASIAGCRIIGRMCVGNRHGL
LVPNNTTDQELQHIRNSLPDTVQIRRVEERLSALGNVTTCNDYVALVHPDLDRETEEILADVLKVEVFRQ
TVADQVLVGSYCVFSNQGGLVHPKTSIEDQDELSSLLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDT
TSTELSVVESVFKLNEAQPSTIATSMRDSLIDSLT

TRRLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_852133
RefSeq Size 1259
RefSeq ORF 735
Synonyms b(2)gcn; CAB; eIF-6; EIF3A; ITGB4BP; p27(BBP); p27BBP
Locus ID 3692
UniProt ID P56537
Cytogenetics 20q11.22
Summary Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. provided by RefSeq, Jun 2012
Protein Families Druggable Genome
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Other "Integrin beta 4 binding protein" proteins (3)
SKU Description Size Price
LC405776 Lyophilized EIF6 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY405776 Transient overexpression lysate of eukaryotic translation initiation factor 6 (EIF6), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP320391 Recombinant protein of human eukaryotic translation initiation factor 6 (EIF6), transcript variant 2, 20 µg 20 ug
$737.00

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