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ULK3 (NM_001099436) Human Mass Spec Standard

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SKU
PH320209
ULK3 MS Standard C13 and N15-labeled recombinant protein (NP_001092906)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA326685 Rabbit Polyclonal ULK3 Antibody
100 ug
$640.00
LY420458 Transient overexpression lysate of unc-51-like kinase 3 (C. elegans) (ULK3) (as WB positive control) 100 ug
$665.00

Other products for "ULK3 or NM_001099436"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220209
Predicted MW 53.3 kDa
Protein Sequence
Protein Sequence
>RC220209 representing NM_001099436
Red=Cloning site Green=Tags(s)

MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIR
HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKP
QNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQ
PPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGES
LGRATALVVQAVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSS
SNQALLRQGTSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPG
RRRELLHTEVQNLMARAEYLKEQVKMRESRWEADTLDKEGLSESVRSSCTLQ

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001092906
RefSeq Size 2635
RefSeq ORF 1416
Locus ID 25989
UniProt ID Q6PHR2
Cytogenetics 15q24.1
Summary Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome, Protein Kinase
Protein Pathways mTOR signaling pathway, Regulation of autophagy
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Other "ULK3" proteins (3)
SKU Description Size Price
LC420458 Lyophilized ULK3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY420458 Transient overexpression lysate of unc-51-like kinase 3 (C. elegans) (ULK3) (as WB positive control) 100 ug
$665.00
TP320209 Recombinant protein of human unc-51-like kinase 3 (C. elegans) (ULK3), 20 µg 20 ug
$867.00

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