DUSP18 (NM_152511) Human Mass Spec Standard

SKU
PH319496
DUSP18 MS Standard C13 and N15-labeled recombinant protein (NP_689724)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219496
Predicted MW 20.9 kDa
Protein Sequence
Protein Sequence
>RC219496 representing NM_152511
Red=Cloning site Green=Tags(s)

MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVP
VADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI
IRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_689724
RefSeq Size 2453
RefSeq ORF 564
Synonyms DSP18; DUSP20; LMWDSP20
Locus ID 150290
UniProt ID Q8NEJ0
Cytogenetics 22q12.2
Summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 PubMed 19228121).supplied by OMIM, Dec 2009
Protein Families Druggable Genome, Phosphatase
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Other "DUSP18" proteins (3)
SKU Description Size Price
LC407513 Lyophilized DUSP18 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY407513 Transient overexpression lysate of dual specificity phosphatase 18 (DUSP18) (as WB positive control) 100 ug
$436.00
TP319496 Recombinant protein of human dual specificity phosphatase 18 (DUSP18), 20 µg 20 ug
$867.00

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