EDARADD (NM_080738) Human Mass Spec Standard

CAT#: PH319198

EDARADD MS Standard C13 and N15-labeled recombinant protein (NP_542776)

Request Larger Size Package

USD 1,995


Availability*
3 Weeks

Size
    • 10 ug

Product images

Specifications

Product Data
Description EDARADD MS Standard C13 and N15-labeled recombinant protein (NP_542776)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219198
Predicted MW 23.5 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_542776
RefSeq Size 2891
RefSeq ORF 615
Synonyms ECTD11A; ECTD11B; ED3; EDA3
Locus ID 128178
Cytogenetics 1q42.3-q43
Summary This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents