A1CF (NM_138932) Human Mass Spec Standard

CAT#: PH316861

A1CF MS Standard C13 and N15-labeled recombinant protein (NP_620310)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description A1CF MS Standard C13 and N15-labeled recombinant protein (NP_620310)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC216861
Predicted MW 65 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_620310
RefSeq Size 2152
RefSeq ORF 1782
Synonyms ACF; ACF64; ACF65; APOBEC1CF; ASP
Locus ID 29974
Cytogenetics 10q11.23
Summary Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
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