UPF2 (NM_080599) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC215944 |
| Predicted MW | 147.8 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_542166 |
| RefSeq Size | 5387 |
| RefSeq ORF | 3816 |
| Synonyms | HUPF2; RENT2; smg-3 |
| Locus ID | 26019 |
| UniProt ID | Q9HAU5 |
| Cytogenetics | 10p14 |
| Summary | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. provided by RefSeq, Jul 2008 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "UPF2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC409145 | Lyophilized UPF2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC414488 | Lyophilized UPF2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY409145 | Transient overexpression lysate of UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY414488 | Transient overexpression lysate of UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| TP315944 | Recombinant protein of human UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
Citations
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