PERK (EIF2AK3) (NM_004836) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC214993 |
| Predicted MW | 125.26 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004827 |
| RefSeq Size | 4511 |
| RefSeq ORF | 3348 |
| Synonyms | PEK; PERK; WRS |
| Locus ID | 9451 |
| UniProt ID | Q9NZJ5 |
| Cytogenetics | 2p11.2 |
| Summary | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. provided by RefSeq, Sep 2015 |
| Protein Families | Druggable Genome, Protein Kinase, Secreted Protein, Transmembrane |
| Protein Pathways | Alzheimer's disease |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PERK" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC417724 | EIF2AK3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417724 | Transient overexpression lysate of eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) | 100 ug |
$665.00
|
|
| TP314993 | Recombinant protein of human eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3), 20 µg | 20 ug |
$737.00
|
|
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.