SETD3 (NM_032233) Human Mass Spec Standard

SKU
PH314566
SETD3 MS Standard C13 and N15-labeled recombinant protein (NP_115609)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214566
Predicted MW 67.1 kDa
Protein Sequence
Protein Sequence
>RC214566 representing NM_032233
Red=Cloning site Green=Tags(s)

MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVT
FDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLG
PLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQY
KNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHT
NGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLY
AMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSW
DNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYR
QQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKATENGLVNGENSIP
NGTRSENESLNQESKRAVEDAKGSSSDSTAGVKE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_115609
RefSeq Size 2905
RefSeq ORF 1782
Synonyms C14orf154; hSETD3
Locus ID 84193
UniProt ID Q86TU7
Cytogenetics 14q32.2
Summary Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30526847, PubMed:30626964, PubMed:30785395). Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964). Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964, PubMed:30785395).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other "SETD3" proteins (5)
SKU Description Size Price
LC404739 Lyophilized SETD3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC410259 Lyophilized SETD3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY404739 Transient overexpression lysate of SET domain containing 3 (SETD3), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY410259 Transient overexpression lysate of SET domain containing 3 (SETD3), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP314566 Recombinant protein of human SET domain containing 3 (SETD3), transcript variant 1, 20 µg 20 ug
$867.00

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