NFH (NEFH) (NM_021076) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC213487 |
| Predicted MW | 111.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_066554 |
| RefSeq Size | 3695 |
| RefSeq ORF | 3060 |
| Synonyms | CMT2CC; NFH |
| Locus ID | 4744 |
| UniProt ID | P12036 |
| Cytogenetics | 22q12.2 |
| Summary | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. provided by RefSeq, Oct 2008 |
| Protein Families | Druggable Genome |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "NFH" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC412101 | Lyophilized NEFH HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY412101 | Transient overexpression lysate of neurofilament, heavy polypeptide (NEFH) (as WB positive control) | 100 ug |
$665.00
|
|
| TP313487 | Purified recombinant protein of Homo sapiens neurofilament, heavy polypeptide (NEFH), 20 µg | 20 ug |
$867.00
|
|
| TP762455 | Purified recombinant protein of Human neurofilament, heavy polypeptide (NEFH), Ala778-End, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$240.00
|
|
Citations
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