NFH (NEFH) (NM_021076) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | N-His |
| Predicted MW | 27.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_066554 |
| Locus ID | 4744 |
| UniProt ID | P12036 |
| Cytogenetics | 22q12.2 |
| RefSeq Size | 3695 |
| RefSeq ORF | 3060 |
| Synonyms | CMT2CC; NFH |
| Summary | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. provided by RefSeq, Oct 2008 |
| Protein Categories | Intracellular Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "NFH" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH313487 | NEFH MS Standard C13 and N15-labeled recombinant protein (NP_066554) | 10 ug |
$3,360.00
|
|
| LC412101 | Lyophilized NEFH HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY412101 | Transient overexpression lysate of neurofilament, heavy polypeptide (NEFH) (as WB positive control) | 100 ug |
$665.00
|
|
| TP313487 | Purified recombinant protein of Homo sapiens neurofilament, heavy polypeptide (NEFH), 20 µg | 20 ug |
$867.00
|
|
Citations
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