GADD45B (NM_015675) Human Mass Spec Standard

CAT#: PH313354

GADD45B MS Standard C13 and N15-labeled recombinant protein (NP_056490)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description GADD45B MS Standard C13 and N15-labeled recombinant protein (NP_056490)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213354
Predicted MW 17.6 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_056490
RefSeq Size 1121
RefSeq ORF 483
Synonyms GADD45BETA; MYD118
Locus ID 4616
Cytogenetics 19p13.3
Summary This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008].
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