H2AFY (NM_004893) Human Mass Spec Standard

CAT#: PH310576

H2AFY MS Standard C13 and N15-labeled recombinant protein (NP_004884)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description H2AFY MS Standard C13 and N15-labeled recombinant protein (NP_004884)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210576
Predicted MW 39.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_004884
RefSeq Size 1923
RefSeq ORF 1116
Synonyms H2A.y; H2A/y; H2AF12M; MACROH2A1.1; macroH2A1.2; mH2A1
Locus ID 9555
Cytogenetics 5q31.1
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015].
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