GPS2 (NM_004489) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC210464 |
| Predicted MW | 36.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004480 |
| RefSeq Size | 1181 |
| RefSeq ORF | 981 |
| Synonyms | AMF-1 |
| Locus ID | 2874 |
| UniProt ID | Q13227 |
| Cytogenetics | 17p13.1 |
| Summary | This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GPS2" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC401424 | Lyophilized GPS2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401424 | Transient overexpression lysate of G protein pathway suppressor 2 (GPS2) (as WB positive control) | 100 ug |
$436.00
|
|
| TP310464 | Purified recombinant protein of Homo sapiens G protein pathway suppressor 2 (GPS2), 20 µg | 20 ug |
$737.00
|
|
Citations
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