GRK2 (NM_001619) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC210327 |
| Predicted MW | 79.4 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001610 |
| RefSeq Size | 3603 |
| RefSeq ORF | 2076 |
| Synonyms | ADRBK1; BARK1; BETA-ARK1 |
| Locus ID | 156 |
| UniProt ID | P25098 |
| Cytogenetics | 11q13.2 |
| Summary | This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. provided by RefSeq, Sep 2017 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway, Endocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GRK2" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC419839 | Lyophilized ADRBK1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419839 | Transient overexpression lysate of adrenergic, beta, receptor kinase 1 (ADRBK1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP310327 | Recombinant protein of human adrenergic, beta, receptor kinase 1 (ADRBK1), 20 µg | 20 ug |
$867.00
|
|
Citations
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