STIMATE (NM_198563) Human Mass Spec Standard

SKU
PH308295
TMEM110 MS Standard C13 and N15-labeled recombinant protein (NP_940965)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208295
Predicted MW 33.2 kDa
Protein Sequence
Protein Sequence
>RC208295 protein sequence
Red=Cloning site Green=Tags(s)

MQGPAGNASRGLPGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIW
FLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFG
EYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMF
WVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPL
KPVKKKKHRFGLPV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_940965
RefSeq Size 4746
RefSeq ORF 882
Synonyms TMEM110
Locus ID 375346
UniProt ID Q86TL2
Cytogenetics 3p21.1
Summary Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574). SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:26322679). Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679). Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574). Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).UniProtKB/Swiss-Prot Function
Protein Families Transmembrane
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Other "STIMATE" proteins (3)
SKU Description Size Price
LC404857 Lyophilized TMEM110 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY404857 Transient overexpression lysate of transmembrane protein 110 (TMEM110) (as WB positive control) 100 ug
$436.00
TP308295 Recombinant protein of human transmembrane protein 110 (TMEM110), 20 µg 20 ug
$867.00

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