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GCLC (NM_001498) Human Mass Spec Standard

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SKU
PH307915
GCLC MS Standard C13 and N15-labeled recombinant protein (NP_001489)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA507318 GCLC mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) 100 ul
$447.00
LY419901 Transient overexpression lysate of glutamate-cysteine ligase, catalytic subunit (GCLC) (as WB positive control) 100 ug
$436.00

Other products for "GCLC or NM_001498"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207915
Predicted MW 72.8 kDa
Protein Sequence
Protein Sequence
>RC207915 protein sequence
Red=Cloning site Green=Tags(s)

MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENKKVRLVLS
GEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEANMRKRRKEATSILEENQA
LCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKD
KNTPSPFIETFTEDDEASRASKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALS
AASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTI
DKEIYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLQGMFYFRKDI
CKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCSILNYLK
LIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYSLILKCNQIANELCECPELLGSAFRKVKYSG
SKTDSSN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001489
RefSeq Size 3823
RefSeq ORF 1911
Synonyms GCL; GCS; GLCL; GLCLC
Locus ID 2729
UniProt ID P48506
Cytogenetics 6p12.1
Summary Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.provided by RefSeq, Oct 2010
Protein Families Druggable Genome
Protein Pathways Glutathione metabolism, Metabolic pathways
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Resources
Other "GCLC" proteins (5)
SKU Description Size Price
LC419901 Lyophilized GCLC HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434329 Lyophilized GCLC HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419901 Transient overexpression lysate of glutamate-cysteine ligase, catalytic subunit (GCLC) (as WB positive control) 100 ug
$436.00
LY434329 Transient overexpression lysate of glutamate-cysteine ligase, catalytic subunit (GCLC), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP307915 Recombinant protein of human glutamate-cysteine ligase, catalytic subunit (GCLC), 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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