DOK2 (NM_003974) Human Mass Spec Standard

SKU
PH307621
DOK2 MS Standard C13 and N15-labeled recombinant protein (NP_003965)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207621
Predicted MW 45.4 kDa
Protein Sequence
Protein Sequence
>RC207621 protein sequence
Red=Cloning site Green=Tags(s)

MGDGAVKQGFLYLQQQQTFGKKWRRFGASLYGGSDCALARLELQEGPEKPRRCEAARKVIRLSDCLRVAE
AGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAICLLAFPGQRKELSGPEGKQSRPCMEENELYS
SAVTVGPHKEFAVTMRPTEASERCHLRGSYTLRAGESALELWGGPEPGTQLYDWPYRFLRRFGRDKVTFS
FEAGRRCVSGEGNFEFETRQGNEIFLALEEAISAQKNAAPATPQPQPATIPASLPRPDSPYSRPHDSLPP
PSPTTPVPAPRPRGQEGEYAVPFDAVARSLGKNFRGILAVPPQLLADPLYDSIEETLPPRPDHIYDEPEG
VAALSLYDSPQEPRGEAWRRQATADRDPAGLQHVQPAGQDFSASGWQPGTEYDNVVLKKGPK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003965
RefSeq Size 1870
RefSeq ORF 1236
Synonyms p56DOK; p56dok-2
Locus ID 9046
UniProt ID O60496
Cytogenetics 8p21.3
Summary The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. provided by RefSeq, Jul 2008
Protein Families Druggable Genome
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Other "DOK2" proteins (3)
SKU Description Size Price
LC418321 Lyophilized DOK2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418321 Transient overexpression lysate of docking protein 2, 56kDa (DOK2) (as WB positive control) 100 ug
$436.00
TP307621 Recombinant protein of human docking protein 2, 56kDa (DOK2), 20 µg 20 ug
$737.00

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