SET (NM_003011) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC207606 |
| Predicted MW | 32.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003002 |
| RefSeq Size | 2936 |
| RefSeq ORF | 831 |
| Synonyms | 2PP2A; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; TAF-I; TAF-IBETA |
| Locus ID | 6418 |
| UniProt ID | Q01105 |
| Cytogenetics | 9q34.11 |
| Summary | The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2011 |
| Protein Families | Druggable Genome, Phosphatase, Stem cell - Pluripotency |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "SET" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC401059 | Lyophilized SET HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401059 | Transient overexpression lysate of SET nuclear oncogene (SET), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP307606 | Recombinant protein of human SET nuclear oncogene (SET), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
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