UBE1C (UBA3) (NM_003968) Human Mass Spec Standard

SKU
PH304675
UBA3 MS Standard C13 and N15-labeled recombinant protein (NP_003959)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204675
Predicted MW 51.7 kDa
Protein Sequence
Protein Sequence
>RC204675 representing NM_003968
Red=Cloning site Green=Tags(s)

MADGEEPERKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTC
KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCN
VVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNA
RVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQW
IFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDG
LYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003959
RefSeq Size 2136
RefSeq ORF 1389
Synonyms hUBA3; NAE2; UBE1C
Locus ID 9039
UniProt ID Q8TBC4
Cytogenetics 3p14.1
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
Protein Pathways Ubiquitin mediated proteolysis
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Other "UBE1C" proteins (7)
SKU Description Size Price
PH316801 UBA3 MS Standard C13 and N15-labeled recombinant protein (NP_937838) 10 ug
$3,360.00
LC404973 Lyophilized UBA3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC418315 Lyophilized UBA3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY404973 Transient overexpression lysate of ubiquitin-like modifier activating enzyme 3 (UBA3), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY418315 Transient overexpression lysate of ubiquitin-like modifier activating enzyme 3 (UBA3), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP304675 Recombinant protein of human ubiquitin-like modifier activating enzyme 3 (UBA3), transcript variant 1, 20 µg 20 ug
$867.00
TP316801 Recombinant protein of human ubiquitin-like modifier activating enzyme 3 (UBA3), transcript variant 2, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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