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SETDB1 (NM_012432) Human Mass Spec Standard

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SKU
PH303647
SETDB1 MS Standard C13 and N15-labeled recombinant protein (NP_036564)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA366256 SETDB1 rabbit polyclonal antibody
100 ul
$310.00
LY402212 Transient overexpression lysate of SET domain, bifurcated 1 (SETDB1), transcript variant 2 (as WB positive control) 100 ug
$436.00

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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203647
Predicted MW 143 kDa
Protein Sequence
Protein Sequence
>RC203647 protein sequence
Red=Cloning site Green=Tags(s)

MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQ
KESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDA
GSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRT
KTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGI
VAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKS
GQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKK
STSFRPGSVGSGHSSSTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPVFHGMLERAPA
EPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTP
CGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTT
PPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRL
EECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNF
CKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNK
VASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNK
MSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTA
GQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGES
APVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKIRAGTEL
TWDYNYEVGSVEGKELLCCCGAIECRGRLL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_036564
RefSeq Size 4446
RefSeq ORF 3870
Synonyms ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21
Locus ID 9869
UniProt ID Q15047
Cytogenetics 1q21.3
Summary This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.provided by RefSeq, Jun 2011
Protein Families Druggable Genome
Protein Pathways Lysine degradation
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Other "SETDB1" proteins (7)
SKU Description Size Price
PH326620 SETDB1 MS Standard C13 and N15-labeled recombinant protein (NP_001138887) 10 ug
$3,360.00
LC402212 Lyophilized SETDB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428874 Lyophilized SETDB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402212 Transient overexpression lysate of SET domain, bifurcated 1 (SETDB1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY428874 Transient overexpression lysate of SET domain, bifurcated 1 (SETDB1), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP303647 Purified recombinant protein of Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 2, 20 µg 20 ug
$737.00
TP326620 Recombinant protein of human SET domain, bifurcated 1 (SETDB1), transcript variant 1, 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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