RNF166 (NM_178841) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC203224 |
| Predicted MW | 26.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_849163 |
| RefSeq Size | 1888 |
| RefSeq ORF | 711 |
| Locus ID | 115992 |
| UniProt ID | Q96A37 |
| Cytogenetics | 16q24.2-q24.3 |
| Summary | E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates (PubMed:27880896). In turn, participates in different biological processes including interferon production or autophagy (PubMed:26456228, PubMed:27880896). Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6 (PubMed:26456228). Plays also a role in the early recruitment of autophagy adapters to bacteria (PubMed:27880896). Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication (PubMed:27880896).UniProtKB/Swiss-Prot Function |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "RNF166" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC405857 | Lyophilized RNF166 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY405857 | Transient overexpression lysate of ring finger protein 166 (RNF166), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP303224 | Recombinant protein of human ring finger protein 166 (RNF166), 20 µg | 20 ug |
$867.00
|
|
Citations
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