RNF34 (NM_025126) Human Mass Spec Standard

SKU
PH303191
RNF34 MS Standard C13 and N15-labeled recombinant protein (NP_079402)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203191
Predicted MW 41.6 kDa
Protein Sequence
Protein Sequence
>RC203191 protein sequence
Red=Cloning site Green=Tags(s)

MKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGPFRFTPNPEFSTYPPAATEGPNIVCKACGLSFS
VFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLKVKDLRQYLILRNIPIDTCREK
EDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSFFSNYTAPSATMSSFQGELMDGDQTSRSGVPA
QVQSEITSANTEDDDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNF
VNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCG
KRMSECPICRQYVVRAVHVFKS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_079402
RefSeq Size 2055
RefSeq ORF 1116
Synonyms CARP-1; CARP1; hRFI; RFI; RIF; RIFF
Locus ID 80196
UniProt ID Q969K3
Cytogenetics 12q24.31
Summary The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Feb 2012
Protein Families Druggable Genome
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Other "RNF34" proteins (5)
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LC403050 Lyophilized RNF34 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY403050 Transient overexpression lysate of ring finger protein 34 (RNF34), transcript variant 2 (as WB positive control) 100 ug
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LY403664 Transient overexpression lysate of ring finger protein 34 (RNF34), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP303191 Recombinant protein of human ring finger protein 34 (RNF34), transcript variant 2, 20 µg 20 ug
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