ITM2B (NM_021999) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC202377 |
| Predicted MW | 30.4 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_068839 |
| RefSeq Size | 1896 |
| RefSeq ORF | 798 |
| Synonyms | ABRI; BRI; BRI2; BRICD2B; E3-16; E25B; FBD; imBRI2; RDGCA |
| Locus ID | 9445 |
| UniProt ID | Q9Y287 |
| Cytogenetics | 13q14.2 |
| Summary | Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. provided by RefSeq, Oct 2009 |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ITM2B" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC411840 | Lyophilized ITM2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY411840 | Transient overexpression lysate of integral membrane protein 2B (ITM2B) (as WB positive control) | 100 ug |
$436.00
|
|
| TP302377 | Recombinant protein of human integral membrane protein 2B (ITM2B), 20 µg | 20 ug |
$737.00
|
|
| TP721036 | Purified recombinant protein of Human integral membrane protein 2B (ITM2B) | 10 ug |
$340.00
|
|
Citations
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