ITM2B (NM_021999) Human Mass Spec Standard

SKU
PH302377
ITM2B MS Standard C13 and N15-labeled recombinant protein (NP_068839)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202377
Predicted MW 30.4 kDa
Protein Sequence
Protein Sequence
>RC202377 protein sequence
Red=Cloning site Green=Tags(s)

MVKVTFNSALAQKETKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVIL
GGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADS
DPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIE
NIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_068839
RefSeq Size 1896
RefSeq ORF 798
Synonyms ABRI; BRI; BRI2; BRICD2B; E3-16; E25B; FBD; imBRI2; RDGCA
Locus ID 9445
UniProt ID Q9Y287
Cytogenetics 13q14.2
Summary Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. provided by RefSeq, Oct 2009
Protein Families Druggable Genome, Transmembrane
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Other "ITM2B" proteins (4)
SKU Description Size Price
LC411840 Lyophilized ITM2B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411840 Transient overexpression lysate of integral membrane protein 2B (ITM2B) (as WB positive control) 100 ug
$436.00
TP302377 Recombinant protein of human integral membrane protein 2B (ITM2B), 20 µg 20 ug
$737.00
TP721036 Purified recombinant protein of Human integral membrane protein 2B (ITM2B) 10 ug
$340.00

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