ITM2B (NM_021999) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-His |
| Predicted MW | 23.3 kDa |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Filtered solution of a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
| Reconstitution Method | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_068839 |
| Locus ID | 9445 |
| UniProt ID | Q9Y287 |
| Cytogenetics | 13q14.2 |
| RefSeq Size | 1896 |
| RefSeq ORF | 798 |
| Synonyms | ABRI; BRI; BRI2; BRICD2B; E3-16; E25B; FBD; imBRI2; RDGCA |
| Summary | Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. provided by RefSeq, Oct 2009 |
| Protein Categories | Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ITM2B" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302377 | ITM2B MS Standard C13 and N15-labeled recombinant protein (NP_068839) | 10 ug |
$3,360.00
|
|
| LC411840 | Lyophilized ITM2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY411840 | Transient overexpression lysate of integral membrane protein 2B (ITM2B) (as WB positive control) | 100 ug |
$436.00
|
|
| TP302377 | Recombinant protein of human integral membrane protein 2B (ITM2B), 20 µg | 20 ug |
$737.00
|
|
Citations
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