ILF2 (NM_004515) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC201751 |
| Predicted MW | 43.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004506 |
| RefSeq Size | 1934 |
| RefSeq ORF | 1170 |
| Synonyms | NF45; PRO3063 |
| Locus ID | 3608 |
| UniProt ID | Q12905 |
| Cytogenetics | 1q21.3 |
| Summary | The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. provided by RefSeq, Dec 2014 |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ILF2" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC401437 | Lyophilized ILF2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401437 | Transient overexpression lysate of interleukin enhancer binding factor 2, 45kDa (ILF2) (as WB positive control) | 100 ug |
$436.00
|
|
| TP301751 | Recombinant protein of human interleukin enhancer binding factor 2, 45kDa (ILF2), 20 µg | 20 ug |
$737.00
|
|
Citations
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