RFC2 (NM_002914) Human Mass Spec Standard

SKU
PH301138
RFC2 MS Standard C13 and N15-labeled recombinant protein (NP_002905)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201138
Predicted MW 35.2 kDa
Protein Sequence
Protein Sequence
>RC201138 protein sequence
Red=Cloning site Green=Tags(s)

MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVP
NIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNAS
DKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFG
FINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKL
EFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002905
RefSeq Size 1657
RefSeq ORF 960
Synonyms RFC40
Locus ID 5982
UniProt ID P35250
Cytogenetics 7q11.23
Summary This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. provided by RefSeq, Jul 2013
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways DNA replication, Mismatch repair, Nucleotide excision repair
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Resources
Other "RFC2" proteins (6)
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LC405777 Lyophilized RFC2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419017 Lyophilized RFC2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY405777 Transient overexpression lysate of replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 1 (as WB positive control) 100 ug
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LY419017 Transient overexpression lysate of replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP301138 Recombinant protein of human replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 2, 20 µg 20 ug
$737.00
TP320036 Purified recombinant protein of human replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20 µg 20 ug
$737.00

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