BAD (NM_004322) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200634 |
| Predicted MW | 18.2 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004313 |
| RefSeq Size | 1127 |
| RefSeq ORF | 504 |
| Synonyms | BBC2; BCL2L8 |
| Locus ID | 572 |
| UniProt ID | Q92934 |
| Cytogenetics | 11q13.1 |
| Summary | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. provided by RefSeq, Dec 2019 |
| Protein Families | Druggable Genome |
| Protein Pathways | Acute myeloid leukemia, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Insulin signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, VEGF signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "BAD" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC403214 | Lyophilized BAD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418067 | Lyophilized BAD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429193 | Lyophilized BAD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403214 | Transient overexpression lysate of BCL2-associated agonist of cell death (BAD), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY418067 | Transient overexpression lysate of BCL2-associated agonist of cell death (BAD), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY429193 | Transient overexpression lysate of BCL2-associated agonist of cell death (BAD), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300634 | Recombinant protein of human BCL2-associated agonist of cell death (BAD), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP760222 | Recombinant protein of human BCL2-associated agonist of cell death (BAD), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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