AXL Human qPCR Template Standard (NM_021913)

SKU
HK201002
qPCR primer pairs and template standards against Homo sapiens gene AXL
  $410.00
3 Days*
Specifications
Specifications
Product Data
Recommended Application Plasmid of exact quantity for transcript copy number calculation
ACCN NM_021913
UniProt ID P30530
Synonyms ARK; JTK11; Tyro7; UFO
Components 1 vial of lyophilized SybGREEN qPCR primer mix (1 nmol each primer, sufficient for 200 reactions)
1 vial lyophilized Gene Specific qPCR template standard: 50 X 10^7 copies, double-stranded DNA
1 vial containing 1 mL 10x PCR template standard dilution buffer
Quality Control The kit has been tested to generate satisfactory qPCR data on ABI 7900HT
Storage Store at -20°C.
Stability The primer mix and template standard are stable for one year from date of shipping.
Shipping Ambient
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Documents
Resources

file-alt Citations

Epigenetic regulation of AXL and risk of childhood asthma symptoms
Gao, Millstein, Siegmund et al
Clin Epigenetics (2017) 9, 121 DOI: 10.1186/s13148-017-0421-8
Cited by 24
AI Summary: OriGene products, specifically the qStar mRNA detection system and the cDNA synthesis kit (#NP100042), were used to quantify AXL mRNA expression in cord blood samples, supporting the study's investigation into the relationship between AXL gene regulation and childhood asthma risk.
Snippet: mRNA expression in NEST. Origene's qStar mRNA detection system (Origene, Rockville, MD) was used in the quantification of AXL mRNA in cord blood in NEST subjects First strand cDNA conversion of mRNA was performed using Origene's cDNA synthesis kit (#NP100042 Cached
FigureFigure
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
Paolino, Choidas, Wallner et al
Nature (2014)
Cited by 459
AI Summary: OriGene contributed full-length Flag-tagged human TYRO3, AXL, and MER proteins, which were used to study the ubiquitylation of TAM receptors in the investigation of NK cell-mediated anti-metastatic activity.
Snippet: In brief, full-length Flag-tagged human TYRO3, AXL and MER (all from Origene) were incubated at 30 °C for 1 h in a reaction mixture (20 μl) containing ubiquitylation solution (Enzo Biomol)
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
Byers, Diao, Wang et al
Clin Cancer Res (2013) 19 (1), 279-90 DOI: 10.1158/1078-0432.CCR-12-1558
AI Summary: OriGene products, specifically the AXL shRNA (OriGene, TL313415) and AXL cDNA (OriGene, SC119514), were used to manipulate AXL expression in NSCLC cell lines, enabling the authors to investigate the role of AXL in mediating resistance to EGFR inhibitors and to validate AXL as a therapeutic target for overcoming such resistance.
FigureFigure
Showing 1-3 of 3 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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