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VR1 (TRPV1) (NM_080704) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC217653L1V
Lenti ORF particles, TRPV1 (Myc-DDK tagged) - Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1, 200ul, >10^7 TU/mL
  $1,318.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol VR1
Synonyms VR1
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC217653).
ACCN NM_080704
ORF Size 2517 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_080704.2
RefSeq Size 4191 bp
RefSeq ORF 2520 bp
Locus ID 7442
UniProt ID Q8NER1
Cytogenetics 17p13.2
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
MW 95 kDa
Summary Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. provided by RefSeq, Jul 2008
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Documents
Resources

file-alt Citations

Endothelin-1 potentiates TRPV1-mediated vasoconstriction of human adipose arterioles in a protein kinase C-dependent manner
Korishettar, Nishijima, Wang et al
Br J Pharmacol (2021) 178 (3), 709-725 DOI: 10.1111/bph.15324
Cited by 6
AI Summary: In this study, OriGene products—including the TRPV1 antibody (TA322639) and TRPV1 cDNA (RC211598)—were used to detect and confirm TRPV1 mRNA and protein expression in human resistance arteries, supporting the investigation of TRPV1's role in vasomotor function.
Figure
Analgesic effect of dimethyl trisulfide in mice is mediated by TRPA1 and sst4 receptors
Pozsgai, Payrits, Sághy et al
Nitric Oxide (2017)
AI Summary: In this study, the human TRPV1 cDNA clone (TrueClone ID: TC109883) from OriGene was used to investigate the role of TRPV1 in the analgesic effects of dimethyl trisulfide, contributing to the molecular analysis of receptor involvement in pain modulation.
Snippet: TRPV1 receptor. Human TRPA1 cDNA clone was obtained from the Life Technologies CloneRanger collection (clone ID: 100016279). Human TRPV1 cDNA clone was obtained from the OriGene Inc (TrueClone ID:TC109883). ... All 2 versions Cite SaveSaving
Showing 1-2 of 2 papers.
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