SIRPB1 (NM_006065) Human Tagged ORF Clone Lentiviral Particle

SKU RC211765L1V

Lenti ORF particles, SIRPB1 (Myc-DDK tagged) - Human signal-regulatory protein beta 1 (SIRPB1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: SIRPB1
• Synonyms: CD172b; SIRP-BETA-1
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211765).
• ACCN: NM_006065
• ORF Size: 1194 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006065.1
• RefSeq Size: 3804 bp
• RefSeq ORF: 1197 bp
• Locus ID: 10326
• UniProt ID: O00241
• Cytogenetics: 20p13
• Domains: ig, IG, IGc1
• Protein Families: Druggable Genome, Transmembrane
• MW: 43.2 kDa
• Summary: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]