MTMR2 (NM_016156) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | MTMR2 |
| Synonyms | CMT4B; CMT4B1 |
| Vector | pLenti-C-Myc-DDK |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_016156 |
| ORF Size | 1929 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_016156.3 |
| RefSeq Size | 4603 bp |
| RefSeq ORF | 1932 bp |
| Locus ID | 8898 |
| UniProt ID | Q13614 |
| Cytogenetics | 11q21 |
| Domains | GRAM, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism |
| MW | 73.4 kDa |
| Summary | This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. provided by RefSeq, Aug 2011 |
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