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TSPAN12 (NM_012338) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC206943L1V
Lenti ORF particles, TSPAN12 (Myc-DDK tagged) - Human tetraspanin 12 (TSPAN12), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK mGFP DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
  $850.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol TSPAN12
Synonyms EVR5; NET-2; NET2; TM4SF12
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206943).
ACCN NM_012338
ORF Size 915 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_012338.3
RefSeq Size 2579 bp
RefSeq ORF 918 bp
Locus ID 23554
UniProt ID O95859
Cytogenetics 7q31.31
Domains transmembrane4
Protein Families Transmembrane
MW 35.4 kDa
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. provided by RefSeq, Jul 2008
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Documents
Resources

file-alt Citations

Whole-Exome Sequencing Analysis Identified Novel Mutations in the TSPAN12 Gene in Chinese Families with Familial Exudative Vitreoretinopathy
Yuan, Xu, Zhang et al
Genet Test Mol Biomarkers (2019) 23 (10), 722-727 DOI: 10.1089/gtmb.2019.0049
AI Summary: OriGene products, specifically the C-terminal Flag-tagged human TSPAN12 cDNA and wild-type LRP5 cDNA, were used to construct expression plasmids for functional assays investigating the effects of novel TSPAN12 mutations identified in Chinese FEVR families.
Snippet: Construction of expression plasmids C-terminal Flag-tagged human TSPAN12 expression cDNA were purchased from Origene, Inc To construct LRP5 expression plasmid, the cDNA encoding wild-type LRP5 (Origene, Inc.) was sub-cloned in-frame into the pRK5
Showing 1-1 of 1 papers.
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