CARD12 (NLRC4) (NM_021209) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | CARD12 |
| Synonyms | AIFEC; CARD12; CLAN; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; IPAF |
| Vector | pLenti-C-Myc-DDK |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_021209 |
| ORF Size | 3072 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_021209.3 |
| RefSeq Size | 3385 bp |
| RefSeq ORF | 3075 bp |
| Locus ID | 58484 |
| UniProt ID | Q9NPP4 |
| Cytogenetics | 2p22.3 |
| Domains | LRR |
| Protein Pathways | NOD-like receptor signaling pathway |
| MW | 116.2 kDa |
| Summary | This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014 |
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