Integrin beta 5 (ITGB5) (NM_002213) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | Integrin beta 5 |
| Vector | pLenti-C-Myc-DDK |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_002213 |
| ORF Size | 2397 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_002213.3, NP_002204.2 |
| RefSeq Size | 3392 bp |
| RefSeq ORF | 2400 bp |
| Locus ID | 3693 |
| UniProt ID | P18084, L7RT22 |
| Cytogenetics | 3q21.2 |
| Domains | EGF, INB, PSI, VWA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton |
| MW | 88.1 kDa |
| Summary | This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. provided by RefSeq, Aug 2017 |
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