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CTPS2 (NM_001144002) Human Untagged Clone

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SKU
SC325216
CTPS2 (untagged)-Human CTP synthase II (CTPS2), transcript variant 3
  $601.00
3 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CTPS2
Synonyms GATD5B
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>SC325216 representing NM_001144002.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGAAGTACATCCTGGTCACGGGTGGGGTCATCTCAGGCATTGGTAAAGGGATCATTGCCAGCAGCATT
GGAACGATTCTAAAATCATGTGGACTCCGAGTTACTGCCATAAAAATCGACCCCTATATTAACATCGAT
GCTGGCACTTTTTCACCTTATGAACACGGTGAAGTCTTCGTCTTAAATGATGGTGGAGAAGTTGATTTA
GACCTTGGAAATTATGAAAGATTTTTGGATATTAATCTTTATAAAGACAACAATATCACCACGGGGAAG
ATATATCAGCATGTGATCAATAAAGAGAGGCGTGGTGATTACCTGGGGAAAACAGTGCAAGTTGTCCCT
CACATTACTGATGCTGTCCAGGAGTGGGTTATGAATCAAGCCAAGGTGCCGGTGGATGGTAATAAGGAA
GAGCCCCAAATATGCGTTATTGAGCTGGGAGGCACCATTGGAGACATCGAAGGAATGCCGTTTGTGGAG
GCGTTTAGACAATTCCAGTTTAAGGCGAAAAGAGAGAATTTCTGTAATATCCACGTTAGCCTTGTCCCA
CAGCTCAGTGCTACCGGAGAACAAAAAACCAAACCCACCCAAAACAGCGTCCGCGCACTGAGGGGTTTA
GGCCTGTCTCCAGATCTGATTGTCTGCCGAAGTTCAACGCCCATTGAGATGGCCGTGAAGGAGAAGATT
TCTATGTTTTGTCACGTGAACCCTGAACAGGTCATATGTATCCATGATGTTTCTTCCACATACCGAGTT
CCTGTGCTTTTAGAGGAACAAAGCATTGTGAAATATTTTAAGGAGAGATTGCACCTGCCCATCGGTGAT
TCTGCAAGTAATTTGCTTTTTAAGTGGAGAAATATGGCTGACAGGTATGAAAGGTTACAGAAAATATGC
TCCATAGCCCTGGTTGGCAAATACACCAAGCTCAGAGACTGCTACGCCTCTGTGTTCAAAGCCCTGGAA
CACTCAGCCCTGGCCATCAACCACAAGTTGAATCTGATGTACATAGACTCCATTGATCTGGAGAAGATC
ACTGAAACCGAGGACCCTGTGAAATTTCATGAAGCTTGGCAGAAGCTATGCAAAGCTGATGGTATTCTT
GTGCCTGGAGGCTTTGGAATCAGAGGAACATTGGGAAAACTCCAGGCGATTTCTTGGGCAAGGACAAAG
AAGATTCCTTTTCTGGGAGTTTGTCTTGGGATGCAACTAGCAGTGATAGAGTTTGCAAGAAACTGCCTT
AACTTGAAAGATGCTGATTCCACAGAGTTTAGGCCAAATGCCCCAGTTCCTCTGGTGATTGATATGCCC
GAGCACAACCCTGGCAATTTGGGAGGAACAATGAGACTGGGAATAAGAAGAACTGTTTTCAAAACTGAA
AATTCAATATTAAGGAAACTTTATGGTGATGTTCCTTTTATAGAAGAAAGACACAGACATCGGTTCGAG
GTAAACCCTAACCTGATCAAACAATTTGAGCAGAATGACTTAAGTTTTGTAGGTCAGGATGTTGATGGA
GACAGGATGGAAATCATTGAACTGGCAAATCATCCTTATTTTGTTGGTGTCCAGTTCCATCCTGAGTTT
TCTTCTAGGCCGATGAAGCCTTCCCCTCCGTATCTGGGGCTGTTACTTGCAGCAACTGGGAACCTGAAT
GCCTACTTGCAACAGGGTTGCAAACTGTCTTCCAGTGATAGATACAGTGATGCCAGTGATGACAGCTTT
TCAGAGCCAAGGATAGCTGAGTTGGAAATAAGCTGA
ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites SgfI-MluI |
ACCN NM_001144002
Insert Size 1761 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001144002.1
RefSeq Size 4334 bp
RefSeq ORF 1761 bp
Locus ID 56474
UniProt ID Q9NRF8
Cytogenetics Xp22.2
Protein Pathways Metabolic pathways, Pyrimidine metabolism
MW 65.7 kDa
Summary The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013
Transcript Variant: This variant (3) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
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Documents
Resources
"NM_001144002" in other vectors (4)
SKU Description Size Price
RC226565 CTPS2 (Myc-DDK-tagged)-Human CTP synthase II (CTPS2), transcript variant 3 10 ug
$545.00
RC226565L3 Lenti ORF clone of Human CTP synthase II (CTPS2), transcript variant 3, Myc-DDK-tagged 10 ug
$845.00
RC226565L4 Lenti ORF clone of Human CTP synthase II (CTPS2), transcript variant 3, mGFP tagged 10 ug
$845.00
RG226565 CTPS2 (tGFP-tagged) - Human CTP synthase II (CTPS2), transcript variant 3 10 ug
$489.00 $745.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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