PTP4A1 (NM_003463) Human Untagged Clone
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PTP4A1 |
| Synonyms | HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_003463 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_003463.3, NP_003454.1 |
| RefSeq Size | 5099 bp |
| RefSeq ORF | 522 bp |
| Locus ID | 7803 |
| UniProt ID | Q93096 |
| Cytogenetics | 6q12 |
| Domains | PTPc_motif, Y_phosphatase |
| Protein Families | Druggable Genome, Phosphatase |
| Summary | This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. provided by RefSeq, Jun 2013 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_003463" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC200435 | PTP4A1 (Myc-DDK-tagged)-Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1) | 10 ug |
$300.00
|
|
| RC200435L1 | Lenti ORF clone of Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC200435L2 | Lenti ORF clone of Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1), mGFP tagged | 10 ug |
$600.00
|
|
| RC200435L3 | Lenti ORF clone of Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC200435L4 | Lenti ORF clone of Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1), mGFP tagged | 10 ug |
$600.00
|
|
| RG200435 | PTP4A1 (tGFP-tagged) - Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1) | 10 ug |
$489.00
$500.00
|
|
| SC117949 | PTP4A1 (untagged)-Human protein tyrosine phosphatase type IVA, member 1 (PTP4A1) | 10 ug |
$300.00
|
|
Citations
Dynamic Regulation of miRNA Expression by Functionally Enhanced Placental Mesenchymal Stem Cells PromotesHepatic Regeneration in a Rat Model with Bile Duct Ligation
Kim, Jun, Park et al
Int J Mol Sci (2019) 20 (21) DOI: 10.3390/ijms20215299
Kim, Jun, Park et al
Int J Mol Sci (2019) 20 (21) DOI: 10.3390/ijms20215299
Cited by 26
AI Summary: In this study, OriGene’s PRL-1 plasmid (containing the CMV6-AC vector and neomycin resistance) was used to overexpress PRL-1 in placental mesenchymal stem cells, enabling the researchers to investigate the enhanced therapeutic mechanisms of these modified cells in promoting liver regeneration.
Snippet: …Louis, MO, USA), and 1% penicillin/streptomycin (P/S;Gibco). To overexpress human PRL-1 (phosphatase of regenerating liver-1;protein tyrosine phosphatase type 4 A, member 1;PTP4A1) in naïve PD-MSCs, a PRL-1 plasmid containing the CMV6-AC vector and antibiotic neomycin for mammalswas obtained from Origene(Origene Inc., Rockville, MD, US
Dynamic Regulation of miRNA Expression by Functionally Enhanced 3 Placental Mesenchymal Stem Cells Promotes Hepatic Regeneration in a 4 Rat Model with Bile Duct Ligation
Kim, Jun, Park et al
Preprints (2019)
Kim, Jun, Park et al
Preprints (2019)
Snippet: PTP4A1) in naïve PD-MSCs, a PRL-1 plasmid containing the CMV6-AC vector and antibiotic 327 neomycin for mammals was obtained from Origene (Origene Inc., Rockville, MD, USA). Naïve PDMSCs (5x105 328 cells/cuvette) were transfected using the 4D AMAXA Nucleofector system (Lonza, 329 Basel, Switzerland). …
Showing 1-2 of 2 papers.
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